Last update
4/6/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.3
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.6
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A (from Retinyl Palmitate and Fish Liver Oil)
3,000 mcg
333%
Top Medical Research Studies
9.5
We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.
Read More
7
We explored the effects of all-trans retinoic acid (ATRA) when combined with dexamethasone and alpha-interferon in treating advanced multiple myeloma. Out of 10 treated patients, eight completed the regimen.
Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.
Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.
Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
Read More
Most Useful Reviews
7.5
Supports bones and muscles
Good for bones and muscles, tastes pleasant, and serves as an excellent source of vitamin A for the body.
Read More
6
Boosts bone health
100 people found this helpful
Excellent quality! Vitamin D3 is essential for health, especially with limited sunlight. It improves immunity and positively impacts bone health due to its easy absorption. The capsule size is convenient, and there's plenty in the packaging.
Read More
7
Improved recovery
2 people found this helpful
I bought this product for sleep issues and was amazed by its impact on my mood and energy. It significantly improved my sleep quality and muscle recovery, especially after healing broken bones. I’m very satisfied with the results.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.3
- All Researches
9.5
We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.
Read More
7
We explored the effects of all-trans retinoic acid (ATRA) when combined with dexamethasone and alpha-interferon in treating advanced multiple myeloma. Out of 10 treated patients, eight completed the regimen.
Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.
Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.
Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Supports bones and muscles
Good for bones and muscles, tastes pleasant, and serves as an excellent source of vitamin A for the body.
Read More
6
Boosts bone health
100 people found this helpful
Excellent quality! Vitamin D3 is essential for health, especially with limited sunlight. It improves immunity and positively impacts bone health due to its easy absorption. The capsule size is convenient, and there's plenty in the packaging.
Read More
7
Improved recovery
2 people found this helpful
I bought this product for sleep issues and was amazed by its impact on my mood and energy. It significantly improved my sleep quality and muscle recovery, especially after healing broken bones. I’m very satisfied with the results.
Read More
7.5
Skin and bone improvement
Excellent! It enhances skin condition, vision, and bones, prolongs youth, boosts immunity against infections, and protects mucous membranes from pollution, which is crucial for city dwellers.
Read More
7.5
Strengthens hair and bones
More hair and healthier bones! Vitamin A is well-known for strengthening hair and nails; in this quantity, it's also vital for bone health.
Read More
Frequently Asked Questions
7.5
Strengthens hair and bones
More hair and healthier bones! Vitamin A is well-known for strengthening hair and nails; in this quantity, it's also vital for bone health.
7.5
Skin and bone improvement
Excellent! It enhances skin condition, vision, and bones, prolongs youth, boosts immunity against infections, and protects mucous membranes from pollution, which is crucial for city dwellers.
7.5
Supports bone health
16 people found this helpful
Vitamin A is crucial for the aging process, cell growth, and the formation of bones and teeth. It's fat-soluble, making absorption more effective. I advise taking 1 tablet every 2-3 days for optimal benefits and combining it with Folic Acid and Vitamin E for enhanced effects on skin, hair, and nails.
9.5
We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.
7
We explored the effects of all-trans retinoic acid (ATRA) when combined with dexamethasone and alpha-interferon in treating advanced multiple myeloma. Out of 10 treated patients, eight completed the regimen.
Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.
Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.
Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
References
- Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102:556. 10.1136/archdischild-2016-310631
- Musto P, Sajeva MR, Sanpaolo G, D'Arena G, Scalzulli PR, et al. All-trans retinoic acid in combination with alpha-interferon and dexamethasone for advanced multiple myeloma. Haematologica. 1997;82:354. PubMed
Data last updated:
