We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.
Read More
7
ATRA shows mixed effects on pain
All-trans retinoic acid in combination with alpha-interferon and dexamethasone for advanced multiple myeloma.
We explored the effects of all-trans retinoic acid (ATRA) when combined with dexamethasone and alpha-interferon in treating advanced multiple myeloma. Out of 10 treated patients, eight completed the regimen.
Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.
Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
Read More
Most Useful Reviews
9
Alleviates throat pain
7 people found this helpful
When experiencing throat discomfort, I take 5 tablets of Vitamin A at once. After this, there is no throat pain the following day. Increasing the dosage is key when any discomfort arises; hence, I recommend it if you're suffering from throat pain.
Read More
9
Essential for growth
6 people found this helpful
This dietary supplement from Now Foods is excellent for promoting bone growth and supports vision and immune health. Given our diet sometimes lacks adequate vitamin A, a supplement can be an ideal solution when needed.
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9
Eases eye pain
3 people found this helpful
Suffering from eye pain and dryness for years, I turned to this supplement, combining it with Vitamin E. After just five days, I noticed an improvement; the pain and dryness dissipated. Although the tablets are large, they are easily swallowed, and I highly recommend them for overall eye health.
We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.
Read More
7
ATRA shows mixed effects on pain
All-trans retinoic acid in combination with alpha-interferon and dexamethasone for advanced multiple myeloma.
We explored the effects of all-trans retinoic acid (ATRA) when combined with dexamethasone and alpha-interferon in treating advanced multiple myeloma. Out of 10 treated patients, eight completed the regimen.
Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.
Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 25 Reviews
7.6
All Reviews
Positive Reviews
Negative Reviews
9
Alleviates throat pain
7 people found this helpful
When experiencing throat discomfort, I take 5 tablets of Vitamin A at once. After this, there is no throat pain the following day. Increasing the dosage is key when any discomfort arises; hence, I recommend it if you're suffering from throat pain.
Read More
9
Essential for growth
6 people found this helpful
This dietary supplement from Now Foods is excellent for promoting bone growth and supports vision and immune health. Given our diet sometimes lacks adequate vitamin A, a supplement can be an ideal solution when needed.
Read More
9
Eases eye pain
3 people found this helpful
Suffering from eye pain and dryness for years, I turned to this supplement, combining it with Vitamin E. After just five days, I noticed an improvement; the pain and dryness dissipated. Although the tablets are large, they are easily swallowed, and I highly recommend them for overall eye health.
Read More
9
Enhances bone growth
2 people found this helpful
Vitamin A is vital for the body, involved in many processes, including the formation of the skeletal system and teeth. It helps maintain immunity and fights viral infections. This vitamin encourages the growth of bone tissue, prevents rickets, and promotes skin health, making it essential for both children and adults.
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9
Excellent effect
I used it for a certain period, but my doctor advised against taking it during pregnancy due to potential side effects like dry skin, bone pain, and dry eyes. I felt apprehensive and stopped, but before that, I found it to be highly effective, similar to Roaccutane.
Bone pain is a discomfort or ache that originates within the bones themselves and can range from mild to severe. It is different from muscle or joint pain, as it directly affects the skeletal structure. Bone pain can be caused by a variety of factors, including injuries, medical conditions such as osteoarthritis or osteoporosis, infections, or tumors. Symptoms may vary depending on the underlying cause but often include a dull, penetrating ache that may worsen with movement or pressure.
If you're experiencing persistent bone pain, it’s essential to consult with a healthcare professional for a proper diagnosis and treatment plan. Imaging tests like X-rays, MRI, or CT scans may be utilized to determine the root cause of the pain. Treatment can vary widely, ranging from medications to alleviate pain and inflammation to physical therapy or, in some cases, surgical interventions. Understanding the underlying cause is crucial to effectively managing bone pain and ensuring the best path to recovery.
Vitamin A is a fat-soluble vitamin that's essential for several critical bodily functions, including vision, immune response, and cell differentiation. It comes in two primary forms: preformed vitamin A (retinol) found in animal products like liver, fish, and dairy, and provitamin A carotenoids, primarily found in colorful fruits and vegetables such as carrots, sweet potatoes, and spinach. The body can convert carotenoids into retinol, making these plant sources a valuable dietary option, especially for those following a vegetarian or vegan lifestyle.
Aside from its role in maintaining healthy vision—particularly in low-light conditions—vitamin A plays a significant role in skin health and the functioning of the heart, lungs, and kidneys. It also supports the immune system by promoting the development and function of white blood cells. While it's uncommon to experience a deficiency in countries where a balanced diet is accessible, a lack of vitamin A can lead to serious health problems, including night blindness and increased susceptibility to infections. In contrast, excessive intake of vitamin A, particularly through supplements, can be toxic and lead to several health issues, making it crucial to maintain a balanced intake.
Based on user reviews, the time frame for experiencing results from taking a bone health supplement can vary. Some users have reported noticeable improvements within just a few days, particularly when addressing related concerns such as joint and bone pain. For instance, one user mentioned observing a slight improvement in joint and bone pain after following a routine with the supplement for a month Read Review.
However, others have indicated a longer commitment to see significant benefits. Generally, users recommend consistent use over several weeks to gauge the full effects on bone pain and overall health. A user who combined the supplement with vitamin E for enhanced benefits reported positive results, but specifics on timing were not detailed Read Review. Overall, while some may see earlier improvements, a month of regular intake is frequently noted as a good starting point to assess effectiveness in alleviating bone-related discomfort.
The efficacy of supplements in alleviating bone pain appears to be mixed, based on recent scientific research. For instance, a study focused on a case that linked high doses of vitamin A to severe bone pain. This case illustrated that excessive vitamin A intake can lead to significant musculoskeletal issues, including bone pain, which improved markedly upon cessation of the supplement [1]. This suggests that while vitamin A is essential at safe levels, its overconsumption can lead to adverse effects, including bone discomfort.
In another context, the potential of all-trans retinoic acid (ATRA) was evaluated in treating bone pain associated with advanced multiple myeloma. Among patients treated with ATRA combined with other medications, some reported improvements in bone pain during the regimen. However, the overall response was varied, with only two patients showing lasting improvement, indicating that while there may be some therapeutic benefits, the evidence is not robust enough to imply that ATRA is a definitive solution for bone pain [2]. Therefore, more comprehensive research is warranted to ascertain the full extent of these supplements' impact on bone pain relief.
Based on user reviews, many individuals have reported notable improvements in their symptoms after taking vitamin A supplements. For instance, one user mentioned that their throat discomfort vanished overnight after increasing their dosage of vitamin A, specifically citing that the supplement effectively alleviated their throat pain Read Review. Others have experienced benefits for their eyes, with one user combining vitamin A with vitamin E and noticing a significant reduction in pain and dryness within just five days Read Review. Another reported that the supplement helped alleviate discomfort related to mouth pain, leading to a remarkable improvement by the next morning Read Review.
Additionally, users have highlighted the role of vitamin A in promoting bone health. Several reviewers emphasized improvements in their overall well-being, with one individual noting a slight reduction in joint and bone pain after incorporating the supplement into their routine for a month Read Review. Another user expressed satisfaction with hair and bone health enhancements, while others mentioned its positive effects on skin condition and immunity Read ReviewRead Review. While these testimonials indicate substantial benefits, it's essential to remember that individual results may vary depending on personal health conditions and dosage.
Users report mixed experiences when it comes to combining this bone health supplement with others for alleviating bone pain. One reviewer noted a positive outcome from taking vitamin A alongside vitamin E, stating that they observed significant improvements in pain relief and overall comfort within just five days of this combination Read Review. Similarly, another user recommended pairing vitamin A with Folic Acid and vitamin E for enhanced benefits on skin, hair, and nails, which indirectly suggests a holistic approach that may also support bone health Read Review.
Additionally, one user shared their routine of taking vitamin A for a month, followed by a month off, and experienced noticeable improvements in joint and bone pain during that time Read Review. Overall, while some users found success in combining vitamin A with other supplements for better results related to bone pain, they also highlighted the importance of monitoring individual responses to find the most effective regimen.
Based on user reviews, there isn't a clearly defined "right dose" of Vitamin A specifically for treating bone pain, as experiences vary widely among individuals. Some users indicated the importance of moderation and suggested lower doses to prevent toxicity. For example, one user mentioned taking one tablet every 2-3 days combined with other vitamins for optimal benefits on bone and skin health Read Review. Conversely, another review notes a routine of taking one pill daily with a fatty meal, followed by a break to avoid fat accumulation, reporting slight improvements in joint and bone pain Read Review.
Further insights suggest that Vitamin A plays a critical role in bone formation and overall health, with users recommending compliance with dosages based on personal health needs and possibly under medical advice Read Review. Overall, while many recognized its benefits for bone health, the exact dosages needed to treat bone pain effectively appear to depend on individual circumstances and should be considered with caution.
7.5
Slight improvement
This is my first experience with vitamin A. I take one pill each day with a fatty meal for a month, followed by a month off to prevent fat storage. I've noticed a slight improvement in my joint and bone pain since starting this routine.
7.5
Recommended for skin
13 people found this helpful
Recognising the importance of vitamin A, I chose this one due to its good dose and price. It aids skin appearance and bone growth, slowing the aging process. I've been taking it alongside vitamin E for enhanced benefits and wholeheartedly recommend it.
9
Alleviates throat pain
7 people found this helpful
When experiencing throat discomfort, I take 5 tablets of Vitamin A at once. After this, there is no throat pain the following day. Increasing the dosage is key when any discomfort arises; hence, I recommend it if you're suffering from throat pain.
9
Eases eye pain
3 people found this helpful
Suffering from eye pain and dryness for years, I turned to this supplement, combining it with Vitamin E. After just five days, I noticed an improvement; the pain and dryness dissipated. Although the tablets are large, they are easily swallowed, and I highly recommend them for overall eye health.
7.5
Relieves mouth pain
1 people found this helpful
I occasionally suffer from pain and bitterness in my mouth, often making it difficult to drink water. After trying Vitamin A, I felt significantly better the next morning, alleviating the discomfort I experienced.
7.5
Strengthens hair and bones
More hair and healthier bones! Vitamin A is well-known for strengthening hair and nails; in this quantity, it's also vital for bone health.
7.5
Skin and bone improvement
Excellent! It enhances skin condition, vision, and bones, prolongs youth, boosts immunity against infections, and protects mucous membranes from pollution, which is crucial for city dwellers.
7.5
Supports bone health
16 people found this helpful
Vitamin A is crucial for the aging process, cell growth, and the formation of bones and teeth. It's fat-soluble, making absorption more effective. I advise taking 1 tablet every 2-3 days for optimal benefits and combining it with Folic Acid and Vitamin E for enhanced effects on skin, hair, and nails.
6
Vital for bones
106 people found this helpful
Vitamin A is crucial for bone tissue growth and renewal as well as vision improvement. It also bolsters the immune response and regulates metabolism. Excesses can be harmful, but this vitamin is necessary for overall health, while its taste remains neutral.
We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.
7
ATRA shows mixed effects on pain
All-trans retinoic acid in combination with alpha-interferon and dexamethasone for advanced multiple myeloma.
We explored the effects of all-trans retinoic acid (ATRA) when combined with dexamethasone and alpha-interferon in treating advanced multiple myeloma. Out of 10 treated patients, eight completed the regimen.
Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.
Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
References
Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102:556. 10.1136/archdischild-2016-310631
Musto P, Sajeva MR, Sanpaolo G, D'Arena G, Scalzulli PR, et al. All-trans retinoic acid in combination with alpha-interferon and dexamethasone for advanced multiple myeloma. Haematologica. 1997;82:354.